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Thyroxine Sodium

About Thyroxine Sodium

Thyroxine Sodium belongs to 'thyroid agents', primarily used to treat underactive thyroid (hypothyroidism). Hypothyroidism is a chronic disorder, which happens when the thyroid gland (located in the front lower part of the neck), is unable to make enough thyroid hormone. The thyroid gland is responsible for releasing hormones, which are composed of tri-iodothyronine (T3) and thyroxine (T4), which helps the body to regulate and use energy. The thyroid controls functions of the heart and digestive system, without the right amount of these hormones, the body is unable to function properly. Early symptoms of this disease are fatigue and weight gain. While other symptoms include feeling cold even in warm weather, dry skin or too much or too few menses (in women), easy fatigueness, constipation, weight gain,  or even lack of energy. Right diagnosis and treatment of hypothyroid are important to restore normal physical and mental activity.

Thyroxine Sodium contains 'Thyroxine sodium' which replaces or provides more thyroid hormone in the body when the body is unable to naturally produce enough thyroid hormone (Thyroxine) to meet the requirements of the body. In this way, Thyroxine Sodium helps to replace missing thyroid hormone for proper digestion, muscle functioning, brain development, and maintenance of bones.

Take Thyroxine Sodium exactly in the same way as suggested by the doctor. Usually, Thyroxine Sodium does not cause any undesirable effects in the body. Still, its overdose may cause diarrhoea, muscle spasm, weight loss, feeling hot even in cool environments, headache, nervousness, sleeplessness, irritability,  menstrual irregularities (in women), and skin rash. Thus, it is better to take Thyroxine Sodium is the same dose, and if you by chance, miss it then do not double the dose for the sake of getting results fast. If a person experiences any of these signs, then their doctor may suggest them to undertake a blood test called 'thyroid function test' which checks three hormones related to thyroid - TSH, T3, T4 to check if the thyroid gland is functioning normally or not.

Thyroxine Sodium can not be given via mouth in patients dealing with myxedema coma. Your doctor may suggest calcium or vitamin D supplements with Thyroxine Sodium to improve bone density associated with thyroid hormone overreplacement. Consult with your doctor if the symptoms of low thyroid hormone-like weight gain, slow heartbeat, or sensitivity to cold, tiredness, muscle aches, constipation, dry skin, worsens or persists after a couple of days of taking this drug.  If Thyroxine Sodium is taken by persons having diabetes mellitus, then it may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. Thus it is important to carefully monitor the blood glucose level while starting, changing, or stopping thyroid hormone with Thyroxine Sodium. The doctor decides the right dose of Thyroxine Sodium after checking the body weight and thyroid function test report. Regular monitoring of thyroid function is important to check the effectiveness of the medicine.

Uses of Thyroxine Sodium

Hypothyroidism (underactive thyroid) 

Medicinal Benefits

Thyroxine Sodium is a synthetic thyroid hormone that is prescribed for the treatment of underactive thyroid (hypothyroidism). Thyroxine is the important hormone released by the thyroid gland into the bloodstream. It plays an important role in the functioning of the heart, digestion, muscles, and brain development. Thyroxine Sodium acts in the same manner as natural Thyroxine does, as it replaces the natural hormone produced by the thyroid gland so that body has enough thyroxine hormone to regulate the body's needs and metabolism. In this way, it helps to replace missing thyroid hormone and/or to relieve stress on the thyroid gland.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Thyroxine Sodium

  • Heat intolerance
  • Menstrual irregularities
  • Muscle weakness
  • Increased appetite
  • Weight loss
  • Diarrhoea
  • Irregular heartbeat (palpitations)
  • Muscle spasm
  • Headache,
  • Nervousness
  • Irritability
  • Sleeplessness
  • Tremors
  • Skin rash

Patients Concern

Disease/Condition Glossary

Hypothyroidism: It is a chronic condition in which the thyroid gland of the body does not produce enough thyroid hormones to fulfil the needs of the body. The thyroid gland is a small, butterfly-shaped gland that is present at the front of your neck and is responsible for releasing hormones (tri-iodothyronine (T3) and thyroxine (T4)) that is required for the proper functioning of the body. Without enough amount of thyroid hormone, the body’s metabolism slows down, and a person feels less energetic. Early symptoms of hypothyroidism are fatigue, and weight gain and other symptoms include fatigue, weight gain, sensitive face, depression, constipation, feeling cold, decreased sweating, slowed heart rate, elevated blood cholesterol, dry skin, thinning hair, impaired memory, menstrual changes, muscle weakness, muscle stiffness, and hoarseness of voice. It may be possible that there is a loss of Calcium and Vitamin D in some cases of hypothyroidism.

FAQs

The use of Thyroxine Sodium is not suggested in persons who are already dealing with certain medical conditions like thyroid disorder called thyrotoxicosis, untreated or uncontrolled adrenal gland disorder. With it, this medicine can not be used to treat obesity or weight problems. Even before using this medicine, a person should tell their doctor if they have a thyroid nodule, heart disease, a blood clot, or a blood-clotting disorder, diabetes, kidney disease and anemia (lack of red blood cells), osteoporosis, problems with your pituitary gland or any other food or drug allergies.

It is advised to keep taking this Thyroxine Sodium in pregnancy, and don't stop or start it without asking the doctor. If a pregnant woman has low thyroid hormone levels then it could harm both mother and baby so the doctor will change the dose according to the needs of pregnancy.

Every person requires a different amount of thyroid hormone and it varies according to age, sex, and condition (like pregnancy, chronic condition, or complication). Such as, a 30-year-old woman should have a normal TSH of 4.2 mU/L, while a 90-year-old man has a TSH of 8.9 mU/L at their upper limits. Apart from this, Levels of TSH fluctuate due to stress, diet, and medications, and menses period.

The possible symptoms of hypothyroidism are constipation, puffy face, muscle weakness, sudden weight gain, fatigue, increased sensitivity to cold, dry skin, nervousness, or voice hoarseness. If a person notices any such symptoms then they should consult with an Endocrinologist/Physician for further treatment.

This medicine works best when taken without food on an empty stomach at least half an hour before tea/coffee/breakfast in the morning. Ask your doctor before about the right time of taking Thyroxine Sodium.

Yes, Thyroxine Sodium can be advised to children however the dose needs to be adjusted according to the change of weight. If the child loses or gains weight then their doctor will change the dose accordingly.

A Thyroid profile test is suggested by the doctor to check if this medicine is working effectively in the body by checking the levels of T3, T4, and TSH on monthly basis. You will observe a decrease in your TSH level after regular intake of Thyroxine Sodium as prescribed by your doctor.

Thyroxine Sodium is not suggested to use for weight loss purposes as it is only indicated for hypothyroidism.

It is advised to never change or stop taking Thyroxine Sodium as hypothyroidism is usually a lifelong condition. Stopping the medicine on your own can cause an imbalance in the body leading to very serious conditions affecting your metabolism. Consult your doctor for further advice.

If a woman becomes pregnant while taking Thyroxine Sodium, their doctor may make slight changes in dose after doing a thyroid profile test. The doctor may increase the dose of Thyroxine Sodium to meet the high-level thyroid hormone requirement in pregnancy. Treatment of underactive thyroid is vital during pregnancy, as low levels of thyroid hormone in the mother may harm both mother and baby.

It is advised to limit salt intake to less than 2300 mg daily as too much salt intake may increase their blood pressure especially in persons who have an underactive thyroid.

Available Medicines for

Thyroxine Sodium

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